Figure 3.

Functional stability of P2A incubated with human chyme under differing conditions. (A) P2A incubated with mixed human chyme supplemented with 0.1 mM ZnSO₄ (orange squares) or without zinc (blue circles). (B) P2A incubated with human chyme samples collected from five different donors. Chyme 1: pink triangles, Chyme 2: black circles, Chyme 3: green circles, Chyme 4: yellow diamonds, Chyme 5: blue squares. (C). P2A incubated with Chyme 3, pH 5.6 (green circles) or pH-adjusted Chyme 3, pH 7.0 (black squares). Samples were collected over 6 h and assessed for beta-lactamase activity.