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Dissolution of enteric-coated pellets containing P2A (SYN-006). SYN-006 pellets, composed of enteric-coated P2A, were held at low pH (0.1 N HCl) for two h after which the pH was raised to 6.5 (blue squares) or were exposed to pH 6.5 buffer alone (orange circles). (A) Kinetic enzyme dissolution (% release) of P2A enzyme from SYN-006 pellets assessed by ultraviolet (UV) absorbance. (B) Activity (%) of P2A enzyme released from SYN-006 pellets.
