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. 2019 Jan 10;8(1):75. doi: 10.3390/jcm8010075

Figure 5.

Figure 5

Hypoxia inducible factor 1α (HIF-1α) expression in human and murine cell lines. (A) Western blot analysis demonstrating the upregulation of HIF-1α in two human papilloma virus (HPV)-positive cell lines (UPCI-SCC-090 and 93VU147T) and in the murine SCCVII E6/E7 cell line. Concentration of macrophage migration inhibitory factor (MIF) in the culture medium of (B) human HPV-negative cell lines (p <0.001, Student’s t-test), and (C) in human positive cell lines (N.S., Student’s t-test) under normoxic and hypoxic conditions.