Table 3.
Random-effects multivariate analysis of 28-day and in-hospital mortality.
| Variable | 28-Day Mortality | In-Hospital Mortality | ||||
|---|---|---|---|---|---|---|
| Adjusted OR | 95% CI | p | Adjusted OR | 95% CI | p | |
| Vitamin treatment | 0.86 | 0.56–1.33 | 0.51 | 0.69 | 0.44–1.08 | 0.11 |
| Infection focus | ||||||
| Respiratory | Reference | Reference | ||||
| UTI | 0.52 | 0.26–1.04 | 0.06 | 0.36 | 0.18–0.74 | 0.01 |
| Abdomen | 0.73 | 0.45–1.20 | 0.22 | 0.52 | 0.32–0.86 | 0.01 |
| Other | 1.08 | 0.67–1.74 | 0.75 | 0.77 | 0.47–1.25 | 0.29 |
| WBC count (>12,000/μL) | 1.25 | 0.87–1.79 | 0.22 | 1.33 | 0.93–1.92 | 0.12 |
| Creatinine (>2.0 mg/dL) | 0.93 | 0.62–1.40 | 0.73 | 0.84 | 0.55–1.29 | 0.43 |
| Albumin (<3.0 mg/dL) | 3.00 | 2.05–4.39 | <0.01 | 3.29 | 2.13–5.06 | <0.01 |
| Blood culture positive | 0.51 | 0.34–0.76 | <0.01 | 0.67 | 0.45–1.01 | 0.06 |
| Septic shock criteria | 2.16 | 1.36–3.43 | <0.01 | 2.88 | 1.75–4.72 | <0.01 |
| Vasopressor use | 0.25 | 0.14–0.47 | <0.01 | 0.22 | 0.11–0.42 | <0.01 |
| Source control interventions | 0.58 | 0.36–0.93 | 0.02 | 0.55 | 0.34–0.88 | 0.01 |
| Maximum 24-h SOFA score | 1.30 | 1.23–1.37 | <0.01 | 1.31 | 1.23–1.38 | <0.01 |
CI: confidence interval; OR: odds ratio; SOFA: Sequential Organ Failure Assessment; UTI: urinary tract infection; WBC: white blood cell.