Table 4.
Ranking of candidate drugs in each database tested. Ranking was based on the computed enrichment scores and p-values for the candidate drugs for each database. P-values adjusted using the Benjamini-Hochberg Procedure.
| Drug | Cefadroxil |
Propantheline Bromide |
Lanatoside C |
Rifabutin |
DMOG |
Amphotericin B |
||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Rank | P-Value | Rank | P-Value | Rank | P-Value | Rank | P-Value | Rank | P-Value | Rank | P-Value | |
| GO: BP | 409 | 8.47E-06 | 371 | 2.76E-06 | 362 | 9.20E-06 | 263 | 1.03E-06 | 262 | 4.09E-06 | 29 | 1.05E-08 |
| GO: MF | 11 | 2.63E-06 | 142 | 8.25E-04 | 76 | 9.77E-04 | 120 | 2.93E-03 | 30 | 4.92E-08 | 949 | 5.13E-04 |
| GO: CC | 135 | 4.19E-04 | 262 | 4.12E-03 | 205 | 9.99E-04 | 118 | 1.45E-04 | 206 | 5.37E-03 | 379 | 7.47E-03 |
| CP | 675 | 7.57E-03 | 668 | 6.42E-03 | 139 | 7.31E-05 | 186 | 7.31E-05 | 225 | 7.57E-03 | 24 | 1.31E-03 |
| C7 | 14 | 4.70E-03 | 3 | 2.58E-04 | 101 | 3.10E-03 | 121 | 4.45E-03 | 91 | 4.28E-03 | 148 | 7.66E-03 |
| CM | 321 | 1.59E-04 | 454 | 2.36E-06 | 52 | 2.08E-04 | 32 | 7.25E-05 | 181 | 3.06E-03 | 63 | 1.20E-03 |