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. 2018 Jan 23;68(2):280–288. doi: 10.1136/gutjnl-2017-314889

Table 9.

Use of nitrous oxide and oxygen gas, intravenous sedation and intravenous analgesia

SC EAC Difference (one-sided 97.5% CI) Non-inferiority margin or one-sided P value
Nitrous oxide and oxygen gas
 Global 291 (32.9%) 283 (31.9%) −1.0% (−∞ to 3.3%) 10%
 Non-BCSP 209 (43.5%) 180 (36.4%) −7.0% (−∞ to −0.9%) 10%
 BCSP 82 (20.4%) 103 (26.2%) 5.9% (−∞ to 11.7%) 10%
Intravenous sedation
 Global 591 (66.9%) 586 (66.1%) −0.8% (−∞ to 3.6%) 10%
 Non-BCSP 349 (72.6%) 357 (72.3%) −0.3% (−∞ to 5.3%) 10%
 BCSP 242 (60.1%) 229 (58.3%) −1.8% (−∞ to 5.0%) 10%
Intravenous analgesia
 Global 582 (65.8%) 588 (66.3%) 0.5% (−∞ to 4.9%) 10%
 Non-BCSP 342 (71.1%) 360 (72.9%) 1.8% (−∞ to 7.4%) 10%
 BCSP 240 (59.6%) 228 (58.0%) −1.5% (−∞ to −5.3%) 10%

BCSP, Bowel Cancer Screening Programme; EAC, EV-assisted colonoscopy; SC, standard colonoscopy.