Table 1.

Descriptive statistics of the study participants

	Previously naïve	Previously exposed
Number of participants	20	41
Female sex (%)	3 (15.0)	7 (17.1)
Median age, years (range)	34 (21–59)	40 (27–70)
Median cumulative time of residency in an endemic area, years (range)	0 (0–3)	25 (13–39)
Median time since residency in an endemic area, years (range)	–	14 (0–46)
Median time from symptom onset to diagnosis, days (range)	3 (0–12)	3 (1–13)
Median parasitaemia, % infected RBCs (range)	0.9 (< 0.1–8.0)	0.3 (< 0.1–17)
Late treatment failure* (%)	5 (25)	0 (0)
Severe malaria† (%)	1 (5)	4 (9.7)
Treated in intensive care unit (%)	1 (5)	2 (4.9)
Initial intraveneous artesunate treatment (%)	6 (30)	10 (24.4)

*Presented with recrudescent parasitaemia and fever 20–28 days following initial treatment

^†Severe malaria was defined according to the WHO classification