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. 2019 Jan 29;16:2. doi: 10.1186/s12950-019-0206-2

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Gene expression of pro and anti-inflammatory factors in the synovium of AIA rabbits after TOFA treatment. Gene expression analysis of TNF, IL6, IL1β, IFNγ and IL10 in the rabbit synovium. Data is shown as the mean and SEM (n = 16 paws per group). * p < 0.05 vs. Control, # p < 0.05 vs. AIA. AIA: antigen induced arthritis; TOFA: tofacitinib; TNF: tumor necrosis factor; IL: interleukin; IFN: interferon