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. 2019 Jan 29;16:2. doi: 10.1186/s12950-019-0206-2

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Gene expression of metalloproteinases in the synovium of AIA rabbits after TOFA treatment. Gene expression analysis of MMP-1, MMP-3 and MMP-13 in the rabbit synovium. Data is shown as the mean and SEM (n = 16 paws per group). * p < 0.05 vs. Control, # p < 0.05 vs. AIA. AIA: antigen induced arthritis; TOFA: tofacitinib; MMP: metalloproteinase