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. 2019 Apr;14(4):683–691. doi: 10.4103/1673-5374.247472

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Copyright: © Neural Regeneration Research

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Effect of QZS on morphological parameters of sciatic nerves in injured rats.

(A) Axon diameter: 2 and 4 weeks after surgery, axon diameters were significantly greater in the sham group than in the NCI and NCI + QZS groups, and greater in rats treated with QZS than in rats without treatment. At 8 weeks after surgery, the axon diameter was significantly greater in the sham group than in the NCI and NCI + QZS groups. (B) Fiber diameter: 2 weeks after surgery, fiber diameter was significantly greater in the sham group than in the NCI and NCI + QZS groups, and larger in the NCI + QZS group than in the NCI group. At 4 and 8 weeks after surgery, the fiber diameter in the sham group was significantly greater than in the NCI and NCI + QZS groups. (C) g-ratio: 8 weeks after surgery, the g-ratio in the NCI + QZS group was significantly greater than in the sham group. (D) Myelin thickness: Two weeks after surgery, myelin thickness was significantly greater in the sham group than that in the NCI and NCI + QZS groups, and greater in the NCI + QZS group than in the NCI group. At 4 and 8 weeks after surgery, the myelin thickness in the sham group was significantly greater than in the NCI and NCI + QZS groups. *P < 0.05. Data are expressed as the mean ± SD (n = 6; one-way analysis of variance followed by the least significant difference post hoc test). QZS: Qian-Zheng-San.