REAGENT or RESOURCE	SOURCE	IDENTIFIER
Biological Samples
Dengue Patient Whole Blood	Fundación Valle del Lili	Human Subjects in Medical Research (Protocol # 35460)
Dengue Patient Serum	Fundación Valle del Lili	Human Subjects in Medical Research (Protocol # 35460)
Critical Commercial Assays
Paxgene RNA Kit	PreAnalytiX	CAT#762165
Biomark Microfluidic qPCR Array	Stanford University Human Immune Monitoring Center	Cheow et al. (2015). Multiplexed locus-specific analysis of DNA methylation in single cells. Nat Protocols 10, 619-631.
Dengue Duo Combo Test	SD. Bioline	CAT#11FK45
Plasmonic-gold IgG Avidity Test	Nirmidas Biotech	http://www.nirmidas.com/nirmidas-news/2017/3/1/pgold-zikadengue-iggiga-assay-available
Multiplex rRT-PCR for DENV Serotyping	Pinsky lab	Waggoner et al. (2013). Single-Reaction, Multiplex, Real-Time RT-PCR for the Detection, Quantitation, and Serotyping of Dengue Viruses. PLoS Negl Trop Dis 7, e2116.
ZCD Assay (Zika, Chikungunya, and Dengue RT-PCR)	Pinsky lab	Waggoner et al. (2016). Single-Reaction Multiplex Reverse Transcription PCR for Detection of Zika, Chikungunya, and Dengue Viruses. Emerg Infect Dis 22, 1295-1297.
Deposited Data
Colombia dataset	This paper	GEO:GSE124046
Software and Algorithms
MetaIntegrator	R package	https://cran.r-project.org/web/packages/MetaIntegrator/index.html
Cell Type Enrichment Analysis	R package	Sweeney et al. (2015). A comprehensive time-course–based multicohort analysis of sepsis and sterile inflammation reveals a robust diagnostic gene set. Science Translational Medicine 7, 287ra271.
Deconvolution Analysis (within MetaIntegrator)	R package	Vallania et al. (2018). Leveraging heterogeneity across multiple datasets increases cell-mixture deconvolution accuracy and reduces biological and technical biases. Nature Communications 9 (4735).
Prism 7	Graphpad	https://www.graphpad.com/scientific-software/prism/