Table 3.

Mixed models for each region of interest within the pain network.

	Variable	Fa	p-value	Post hoc	t	p-value	Cohen’s d	r
Left thalamus	Group	7.12	0.012	Early	0.07	0.944
	Phase	1.93	0.154	Intermediate	2.51	0.015b	0.66	0.31
	Group*phase	3.24	0.046	Late	2.34	0.023	0.61	0.29
Left S1	Group	5.48	0.026	Early	−0.18	0.861
	Phase	2.31	0.108	Intermediate	2.55	0.014b	0.67	0.32
	Group*phase	3.56	0.035	Late	2.55	0.013b	0.67	0.32
Left S2	Group	6.05	0.020	Early	−0.07	0.944
	Phase	2.61	0.082	Intermediate	2.67	0.010b	0.70	0.33
	Group*phase	4.65	0.013b	Late	2.72	0.009b	0.71	0.34
Right S2	Group	5.46	0.027	Early	−0.21	0.833
	Phase	2.01	0.144	Intermediate	2.64	0.011b	0.69	0.33
	Group*phase	5.80	0.005b	Late	2.69	0.009b	0.71	0.33
Left insula	Group	3.08	0.090	Early	−0.89	0.378
	Phase	4.89	0.011	Intermediate	1.59	0.118
	Group*phase	4.24	0.019b	Late	2.28	0.026	0.60	0.29
Right insula	Group	4.25	0.048	Early	−0.46	0.647
	Phase	4.33	0.018	Intermediate	1.99	0.052
	Group*phase	4.96	0.010b	Late	2.58	0.012b	0.68	0.32
Left dACC	Group	5.10	0.031	Early	0.07	0.943
	Phase	7.67	0.001	Intermediate	2.42	0.019	0.64	0.30
	Group*phase	4.03	0.023b	Late	2.20	0.032	0.58	0.28
Right dACC	Group	4.58	0.041	Early	−0.36	0.718
	Phase	7.73	0.001	Intermediate	2.39	0.020	0.63	0.30
	Group*phase	4.64	0.014b	Late	2.21	0.031	0.58	0.28
Left caudate	Group	4.49	0.043	Early	0.16	0.876
	Phase	7.12	0.002	Intermediate	1.91	0.062
	Group*phase	2.14	0.127	Late	1.62	0.116
Right caudate	Group	4.21	0.049	Early	0.04	0.971
	Phase	8.01	0.001	Intermediate	1.97	0.054
	Group*phase	2.23	0.117	Late	1.5	0.140
Left putamen	Group	6.71	0.015	Early	−0.04	0.964
	Phase	9.3	≤0.001	Intermediate	2.37	0.021	0.62	0.30
	Group*phase	3.4	0.040	Late	1.86	0.068
Right putamen	Group	7.29	0.011	Early	0.04	0.970
	Phase	8.38	0.001	Intermediate	2.35	0.022	0.62	0.29
	Group*phase	3.56	0.035	Late	2.21	0.031	0.58	0.28

S1: primary somatosensory; S2: secondary somatosensory; dACC: dorsal anterior cingulate cortex.

^aDegrees of freedom for each model, group (1, 29), phase (2, 58), and group*phase (2, 58).

^bp-values that survive false discovery rate correction across all regions investigated.