Table 1.
Table showing transmitters co-localized with adenosine 5’-triphosphate (ATP) in the peripheral and central nervous systems (CNS).
Peripheral nervous system | ||
Sympathetic nerves | ATP + NA + NPY | Westfall et al. (1978) and Burnstock (1990) |
Parasympathetic nerves | ATP + ACh +VIP | Hoyle (1994) |
Sensory-motor | ATP + CGRP + SP | Burnstock (1993) |
NANC enteric nerves | ATP +NO + VIP | Belai and Burnstock (1994) and Burnstock (2001) |
Motor nerves (in early development) | ATP + ACh | Henning (1997) |
Central nervous system | ||
Cortex, caudate nucleus | ATP + ACh | Richardson and Brown (1987) |
Hypothalamus, locus coeruleus | ATP + NA | Sperlágh et al. (1997) and Poelchen et al. (2001) |
Hypothalamus, dorsal horn, retina | ATP + GABA | Jo and Role (2002) |
Mesolimbic system | ATP + DA | Krügel et al. (2013) |
Hippocampus, dorsal horn | ATP + glutamate | Mori et al. (2001) and Fujii (2004) |
Modified from Abbracchio et al. (2009), with permission. ACh, acetylcholine; CGRP, calcitonin gene-related peptide; DA, dopamine; GABA, γ-aminobutyric acid; 5-HT, 5-hydroxytryptamine; NA, noradrenaline; NO, nitric oxide, NPY, neuropeptide Y; SP, substance P; VIP, vasoactive intestinal peptide.