Table 2.
Bronchiectasis | COPD | Asthma | Healthy | P value* | |
Total cells (×106/mL) | 0.62 (0.19–1.74)† | 0.83 (0.16–1.88)† | 0.16 (0.09–0.34)‡§ | 0.08 (0.05–0.21) | <0.001 |
Viability (%) | 82.26 (75.00–91.67)† | 87.75 (73.60–92.95)† | 77.78 (62.30–88.00) | 72.22 (50.00–75.00) | 0.005 |
Neutrophils (%) | 67.50 (41.00–84.25)† | 77.25 (73.00–85.13)† | 58.00 (24.50–72.50)‡ | 28.25 (14.75–63.50) | <0.001 |
Neutrophils (×104/mL) | 43.20 (5.21–164.43)† | 60.35 (13.31–149.70)† | 8.24 (3.12–25.01)§‡ | 3.18 (1.51–5.03) | <0.001 |
Eosinophils (%) | 1.00 (0.50–6.50) | 3.75 (1.13–8.88)† | 2.25 (1.00–11.75)† | 1.00 (0.75–1.25) | 0.016 |
Eosinophils (×104/mL) | 0.75 (0.40–2.76)† | 1.89 (1.03–4.03)† | 0.63 (0.14–3.07)† | 0.09 (0.05–0.23) | <0.001 |
Macrophages (%) | 18.75 (11.00–34.75) | 15.50 (8.50–20.03)† | 25.00 (9.25–39.25) | 29.25 (17.00–63.12) | 0.025 |
Macrophages (×104/mL) | 12.40 (5.94–24.42)† | 9.66 (2.91–18.24) | 4.24 (2.00–7.77)§ | 2.10 (1.42–6.43) | 0.002 |
Lymphocytes (%) | 0.75 (0.00–1.50) | 0.38 (0.00–1.25) | 0.50 (0.00–1.50) | 1.5 (0.25–5.13) | 0.058 |
Lymphocytes (×104 cells/mL) |
0.30 (0.00–1.02) | 0.18 (0.00–0.89) | 0.09 (0.00–0.37) | 0.18 (0.05–0.42) | 0.459 |
Columnar epithelial cells (%) | 1.75 (0.75–10.50) | 0.25 (0.00–2.50)† | 4.50 (1.50–10.75)‡ | 9.50 (4.88–23.63) | <0.001 |
Columnar epithelial cells (×104/mL) | 1.99 (0.48–2.67)‡ | 0.28 (0.00–0.59)† | 1.00 (0.35–1.98)‡ | 0.88 (0.38–2.38) | <0.001 |
Data are presented as median (IQR; Q1–Q3) unless otherwise stated.
*Kruskal-Wallis test.
†P<0.0125 compared with healthy controls.
‡P<0.0125 compared with COPD.
§P<0.0125 compared with bronchiectasis.
COPD, chronic obstructive pulmonary disease.