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. 2019 Jan 28;26(1):23–33. doi: 10.1080/10717544.2018.1531954

Scheme 1.

Scheme 1.

Preparation of an inclusion complex (Hyp-HPβCD) consisting of hypericin and hydroxypropyl-β-cyclodextrin (HPβCD). Empty liposomes are loaded with either hypericin which associates with the hydrophobic tails in the lipid membrane or with Hyp-HPβCD incorporated in the aqueous compartment of liposomes.