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. 2019 Jan 27;34(1):562–576. doi: 10.1080/14756366.2018.1532418

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© 2019 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Scheme 1. — Synthesis of Ibuprofen amides 3–16. (i) EDC, OH-Bt, MeCN, r.t. 24 h.