Scheme 3.
Synthesis of Ibuprofen amides 30–34. (i) EDC, OH-Bt, MeCN, r.t. 12 h, (ii) TFA, CH2Cl2, r.t., 24 h.; (iii) NaBHAc3, NaHCO3, ArCHO, r.t., 24 h.
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.