Blinding of participants and personnel
Person responsible for participant care	Yes / No
Participant	Yes / No
Outcome assessor	Yes / No
Other (please specify)	Yes / No
Low risk: if the participants and the personnel are blinded to treatment allocation and this is described. Unclear risk: if the procedure of blinding is insufficiently described or not described at all. High risk: if blinding of participants and personnel is not performed.	Grade L / U / H
Support for judgement