Comparison 2. Number of participants with > 50% pain relief over 6 hours.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Paracetamol or propacetamol vs placebo	10	1143	Risk Ratio (M‐H, Fixed, 95% CI)	2.86 [2.10, 3.91]
1.1 Paracetamol vs placebo	6	532	Risk Ratio (M‐H, Fixed, 95% CI)	3.65 [2.15, 6.21]
1.2 Propacetamol vs placebo	6	611	Risk Ratio (M‐H, Fixed, 95% CI)	2.40 [1.64, 3.50]
2 Paracetamol or propacetamol vs NSAIDs	5	355	Risk Ratio (M‐H, Fixed, 95% CI)	0.79 [0.66, 0.95]
2.1 Paracetamol vs NSAIDs	3	212	Risk Ratio (M‐H, Fixed, 95% CI)	0.82 [0.66, 1.02]
2.2 Propacetamol vs NSAIDs	2	143	Risk Ratio (M‐H, Fixed, 95% CI)	0.75 [0.56, 1.02]
3 Propacetamol vs opioids	1	40	Risk Ratio (M‐H, Fixed, 95% CI)	0.95 [0.83, 1.09]
4 Paracetamol vs propacetamol	3	361	Risk Ratio (M‐H, Fixed, 95% CI)	0.94 [0.73, 1.20]