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. 2016 May 23;2016(5):CD007126. doi: 10.1002/14651858.CD007126.pub3

Akarsu 2010.

Methods Randomized, double‐blind, parallel, active‐controlled. Pain evaluated up to 6 h after dose administered.
Participants Type of surgery: cesarean section
Paracetamol group
Entered/completing: 40/unclear
Age (mean, SD): 24.2 ± 1.1
Sex (male, %): 0
Control group
Entered/completing: 40/unclear
Age (mean, SD): 24.4 ± 1.2
Sex (male, %): 0
Interventions Paracetamol 1 g IV over 15 min at first complaint of pain
Diclofenac 75 mg IM as above
Outcomes Primary: time to first rescue analgesic (1 mg/kg IM pethidine)
Secondary: VAS pain scores at 30 min, 1, 2, 4 and 6 h; adverse events
Source of funding Not reported
Were treatment groups comparable at baseline? Yes ‐ all P values > 0.05: demographic characteristics, week of pregnancy, newborn's weight, Apgar scores, operation time, time to first postoperative analgesic requirement
Details of preoperative pain Participants with previous continuous analgesic use were excluded
Notes Translated from Turkish using Google Translate
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Used envelopes to randomly divide 2 groups – no additional details given
Allocation concealment (selection bias) Unclear risk No details
Blinding (performance bias and detection bias) 
 All outcomes Unclear risk No details but stated as double‐blinded
Incomplete outcome data (attrition bias) 
 All outcomes Unclear risk No mention of participants dropping out
Selective reporting (reporting bias) Low risk All outcomes in Methods section reported in Results
Size High risk Fewer than 50 participants per arm of the study (40 paracetamol, 40 diclofenac)