Arslan 2011.

Methods	Double‐blind, placebo and active‐controlled, single dose, over 24 h Interventions administered at end of procedure
Participants	Type of surgery: thyroidectomy Paracetamol group Entered/completing: 20/20 Age (mean, SD): 49.2 ± 13.3 Sex (male, %): 10.0% Lornoxicam group Entered/completing: 20/20 Age (mean, SD): 43.9 ± 9.5 Sex (male, %): 20.0% Placebo group Entered/completing: 20/20 Age (mean, SD): 48.7 ± 12.3 Sex (male, %): 15.0%
Interventions	Paracetamol 1 g over 10 min Lornoxicam 8 mg or placebo (100 ml NS) over 10 min
Outcomes	Primary: analgesic consumption (tramadol, n/N) at 0 to 6, 6 to 12 and 12 to 24 h and mg total Secondary: VAS pain scores at 15 min, and 1, 2, 4, 6, 8, 12, 18, and 24 h postoperatively Time to first request for analgesia Adverse events
Source of funding	Not mentioned
Were treatment groups comparable at baseline?	Yes
Details of preoperative pain	Patients using analgesics long‐term were excluded from the study
Notes	Translated from Turkish
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Withdrawal of a card. No further details.
Allocation concealment (selection bias)	Unclear risk	Not mentioned
Blinding (performance bias and detection bias) All outcomes	Unclear risk	Not described
Incomplete outcome data (attrition bias) All outcomes	Low risk	Appears that all participants completed the study and that all data were collected
Selective reporting (reporting bias)	Low risk	All outcomes from Methods section reported in Results section
Size	High risk	60 participants (20 paracetamol, 20 placebo, 20 lornoxicam)