Sanyal 2014.
Methods | Prospective, randomized, double‐blind study, parallel‐group, active control x 24 h | |
Participants | Type of surgery: elective total abdominal hysterectomy with or without bilateral salpingo‐oophorectomy Paracetamol group Entered/completing: not stated Age (mean, SD): not stated Sex (male, %): 0 Diclofenac group Entered/completing: not stated Age (mean, SD): not stated Sex (male, %): 0 |
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Interventions | Paracetamol: 1 g IV postoperatively every 8 h x 24 h Diclofenac: 75 mg IM every 8 h x 24 h |
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Outcomes | Primary: requirement of rescue analgesic (time component not described) Secondary: VAS (scale not mentioned) for pain at least at 4 and 12 h postoperatively, time until first rescue analgesic administration, patient satisfaction score (scale not mentioned), nausea, vomiting, bronchospasm |
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Source of funding | None mentioned | |
Were treatment groups comparable at baseline? | Not described | |
Details of preoperative pain | Not described | |
Notes | — | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | No information |
Allocation concealment (selection bias) | Unclear risk | No information |
Blinding (performance bias and detection bias) All outcomes | Unclear risk | No information |
Incomplete outcome data (attrition bias) All outcomes | Unclear risk | Unclear how many participants completed the study or what method of analysis was used |
Selective reporting (reporting bias) | High risk | No data reported |
Size | High risk | Fewer than 50 participants per arm of the study |