Tuncel 2012.

Methods	Local wound infiltration versus IV paracetamol versus IV lornoxicam 30 min before extubation. Additional analgesia with tramadol and as required pethidine.
Participants	Type of surgery: laparoscopic renal and adrenal surgery Paracetamol group Entered/completing: 20/not reported Age (mean, SD): not reported Sex (male, %): not reported Lornoxicam group Entered/completing: 20/not reported Age (mean, SD): not reported Sex (male, %): not reported
Interventions	Paracetamol 1 g 30 min before extubation, then 5 g in 24 h postop, frequency/timing not reported 0.25% levobupivacaine infiltration to trocar incisions (not included in our analysis) Lornoxicam: 8 mg IV 30 min before extubation and another 8 mg during 24 h postop. Frequency not reported.
Outcomes	Primary: pain VAS scores Secondary: cumulative tramadol and pethidine consumption
Source of funding	Not reported
Were treatment groups comparable at baseline?	Not reported
Details of preoperative pain	Not reported
Notes	Abstract
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Not reported
Allocation concealment (selection bias)	High risk	Not reported, and not stated to be unblinded
Blinding (performance bias and detection bias) All outcomes	High risk	Not stated that study was blinded
Incomplete outcome data (attrition bias) All outcomes	Unclear risk	Unclear how many participants completed the study
Selective reporting (reporting bias)	High risk	Most of the outcomes not reported
Size	High risk	Fewer than 50 participants per arm of the study (20 paracetamol, 20 lornoxicam)