Study	Reason for exclusion
Boland 2003	Wrong comparator: compared blind percutaneous insertion versus image guided
Casey 2003	Non‐randomized controlled study
Fong 2001	Non‐randomized controlled study
Gilbert 2016	Wrong intervention: compared impregnated catheter versus non‐impregnated
Hammes 2015	Wrong study design: incidence case control study
Hockley 2007	Wrong intervention: catheter tip positioning system versus blind positioning
Huraib 1994	Controlled clinical trial design
Keohane 1983	Wrong intervention: compared tunnelled versus untunnelled catheters
King 2010	Non‐randomized controlled study
Larson 1984	Non‐randomized controlled study
Meier 1998	Wrong study design: time series design
Mokrzycki 2006	Non‐randomized controlled study
Moretti 2005	Wrong intervention: antimicrobial central venous catheter coating versus non‐coated central venous catheter
Møller 2005	Wrong intervention: patient education
Nehme 1980	Non‐randomized controlled study
Neuman 1998	Prospective study design with no randomization
Puri 1982	Non‐randomized controlled study
Robinson 2005	Wrong design: prospective quality assurance study
Secola 2011	Initial preliminary pilot data randomized at the unit level
Secola 2012	Randomized at the unit level
Sherertz 1997	Wrong intervention: compared coated catheter versus non‐coated catheter
Soifer 1998	Controlled clinical trial design
Tadokoro 2015	Not a randomized controlled trial design
Taylor 2011	Wrong study design: before‐and‐after intervention study
Tomford 1982	Unable to locate any text or data
Tomford 1984	Non‐randomized controlled study
Treacy 2002	Not a randomized controlled trial design
Ward 2000	Unable to locate any text or data