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. 2017 Jul 7;2017(7):CD006396. doi: 10.1002/14651858.CD006396.pub4

Summary of findings 5. Hearing loss prevention programme compared to audiometric testing (hearing loss).

Hearing loss prevention programme (HLPP) compared to audiometric testing
Patient or population: agricultural students without hearing loss
Settings: agricultural schools
 Intervention: HLPP with information
 Comparison: audiometric testing only
Outcomes Illustrative comparative risks* (95% CI) Relative effect
 (95% CI) No of participants
 (studies) Quality of the evidence
 (GRADE) Comments
Assumed risk Corresponding risk
Audiometric testing only HLPP with information
Hearing loss
 STS ≥ 10 dB loss average over 2, 3, 4 kHz in either ear
 Follow‐up: mean three years 21 per 1000 18 per 1000
 (6 to 49) OR 0.85 
 (0.29 to 2.44) 687
 (1 study, RCT) ⊕⊕⊕⊝
 moderate1  
Hearing loss
 STS ≥ 10 dB hearing loss average over 2, 3, 4 kHz in either ear
 Follow‐up: mean 16 years 149 per 1000 141 per 1000
 (74 to 250) OR 0.94 
 (0.46 to 1.91) 355
 (1 study, RCT) ⊕⊕⊕⊝
 moderate1  
*The basis for the assumed risk (e.g. the median control group risk across studies) is provided in footnotes. The corresponding risk (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI).
 CI: Confidence interval; HLPP; hearing loss prevention programme; OR: Odds ratio; STS: standard threshold shift
GRADE Working Group grades of evidence
High quality: we are very confident that the true effect lies close to that of the estimate of the effect
Moderate quality: we are moderately confident in the effect estimate; the true effect is likely to be close to the estimate of effect, but there is a possibility that it is substantially different
Low quality: our confidence in the effect estimate is limited; the true effect may be substantially different from the estimate of the effect
Very low quality: we have very little confidence in the effect estimate; the true effect is likely to be substantially different from the estimate of effect

1We downgraded one level from high to moderate due to lack of information on randomisation and allocation concealment.