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. 2019 Jan 14;2019(1):CD005431. doi: 10.1002/14651858.CD005431.pub4

6. Risk of optic atrophy.

Study Test intervention No. with outcome/no. in group Control intervention No. with outcome/no. in group Total no. with outcome/total no.
Aminocaproic acid
Crouch 1976 Systemic aminocaproic acid 0/32 Placebo 2/27 2/59
Crouch 1997 Systemic aminocaproic acid 0/29 Topical aminocaproic acid 0/35 0/64
Tranexamic acid
Varnek 1980 Tranexamic acid 1/102 Conservative treatment 0/130 1/232
Cortisone
Zetterstrom 1969 Atropine plus cortisone eyedrops 0/58 Conservative treatment 1/59 1/117
Non‐drug medical interventions
Read 1974 Moderate ambulatory activity, patching and shielding of injured eye NR Bed rest with elevation of the head, bilateral patches and eye shield NR 8/137

NR: not reported.