Comparison 1. Systemic aminocaproic acid versus placebo.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Short‐term visual acuity from 20/20 to 20/40	1		Risk Ratio (M‐H, Fixed, 95% CI)	Totals not selected
2 Long‐term visual acuity between 20/20 and 20/40	2	108	Risk Ratio (M‐H, Fixed, 95% CI)	1.03 [0.82, 1.29]
3 Final visual acuity between 20/20 and 20/40	2	143	Risk Ratio (M‐H, Fixed, 95% CI)	1.05 [0.93, 1.18]
4 Time to resolution of primary hemorrhage (days)			Other data	No numeric data
5 Risk of secondary hemorrhage	6	330	Risk Ratio (M‐H, Fixed, 95% CI)	0.28 [0.13, 0.60]
6 Time to rebleed (days)			Other data	No numeric data
7 Risk of corneal blood stain	1		Risk Ratio (M‐H, Fixed, 95% CI)	Totals not selected
8 Risk of glaucoma or increases in IOP			Other data	No numeric data
8.1 Transient increase in IOP			Other data	No numeric data
8.2 Persistent increase in IOP			Other data	No numeric data
9 Risk of glaucoma or elevated IOP	2	83	Risk Ratio (M‐H, Fixed, 95% CI)	0.38 [0.08, 1.82]
10 Risk of optic atrophy	1		Risk Ratio (M‐H, Fixed, 95% CI)	Totals not selected
11 Adverse effects: nausea or vomiting	3	131	Risk Ratio (M‐H, Fixed, 95% CI)	8.60 [2.09, 35.50]
12 Duration of hospitalization (days)			Other data	No numeric data