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Methane directly stimulates GLP‐1 secretion in L cells. GLP‐1 media content (relative to vehicle control) from mouse GLUTag (A) and human NCI‐H716 (B) cells was examined after a 2‐hour methane treatment. Intracellular cAMP was examined in NCI‐H716 cells after 30‐min methane treatment (C). *= P < .05, **= P < .01
