Table 1.
The demographic and clinical characteristics of alcohol-dependent patients
| Alcohol-dependent patients | Patients with early onset of alcohol abuse 215 (35.07%) | Patients with late onset of alcohol abuse 398 (64.93%) | Total 613 (100.00%) | Statistics |
|---|---|---|---|---|
| Age (years) mean ± SD | 45.12±10.09 | 52.33±9.46 | 49.80±10.27 | t=8.79, df =611, P<0.0001; Student’s t-test |
| Smokers, N (%) | 145 (67.44%) | 225 (56.53%) | 370 (60.36%) | χ2=6.943, df =1, P=0.0084; χ2-test |
| Nonsmokers, N (%) | 70 (32.56%) | 173 (43.47%) | 243 (39.64%) | |
| Males, N (%) | 193 (38.68%) | 306 (61.32%) | 499 (81.40%) | χ2=15.30, df =1, P<0.0001; χ2-test |
| Females, N (%) | 22 (19.30%) | 92 (80.70%) | 114 (18.60%) | |
| Patients with somatic comorbidities, N (%) | 128 (59.53%) | 267 (67.08%) | 395 (64.44%) | χ2=3.473, df =1, P=0.0624; χ2-test |
| Patients with liver disease, N (%) | 125 (58.14%) | 261 (65.58%) | 386 (62.97%) | χ2=3.312, df =1, P=0.0688; χ2-test |
| Patients with psychiatric comorbidities, N (%) | 112 (52.09%) | 167 (41.96%) | 279 (45.51%) | χ2=5.780, df =1, P=0.0162; χ2-test |
| Patients with depression, N (%) | 10 (4.65%) | 24 (6.03%) | 34 (5.55%) | χ2=0.5067, df =1, P=0.4766; χ2-test |
| Platelet 5-HT concentration (nmol/mg protein) mean ± SD | 0.88±0.48 | 0.79±0.48 | 0.82±0.48 | U=38035, df =611, P=0.023; Mann–Whitney test |