. 2019 Jan 24;15:339–347. doi: 10.2147/NDT.S191457

Table 2.

Genotype and allele counts and frequencies of rs13212041 HTR1B gene polymorphism in alcohol-dependent patients subdivided according to the gender and early/late onset of alcohol abuse

HTR1B SNP	Genotype N (%)			Statistics	Allele N (%)		Statistics

rs13212041	CC	CT	TT	df =2	C	T	df =1

Males, N (%)	21 (4.21)	157 (31.46)	321 (64.33)	χ²=2.135, P=0.344; χ²-test	199 (19.94)	799 (80.06)	χ²=1.977, P=0.160; χ²-test
Females, N (%)	6 (5.26)	43 (37.72)	65 (57.02)	χ²=2.135, P=0.344; χ²-test	55 (24.12)	173 (75.88)	χ²=1.977, P=0.160; χ²-test

Early onset of alcohol abuse, N (%)	16 (7.44)	65 (30.23)	134 (62.33)	χ²=7.539, P=0.023; χ²-test	97 (22.56)	333 (77.44)	χ²=1.366, P=0.243; χ²-test
Late onset of alcohol abuse, N (%)	11 (2.76)	135 (33.92)	252 (63.32)	χ²=7.539, P=0.023; χ²-test	157 (19.72)	639 (80.28)	χ²=1.366, P=0.243; χ²-test