Table 2. European ancestry association with MS at regions of the MHC in African Americans.

MHC Region	${\stackrel{-}{\mathit{z}}}_{\mathit{l},\mathit{d}}\left(\mathit{k}\right)-{\stackrel{-}{\mathit{q}}}_{\mathit{d}}\left(\mathit{k}\right)$	${\stackrel{-}{\mathit{z}}}_{\mathit{l},\mathit{c}}\left(\mathit{k}\right)-{\stackrel{-}{\mathit{q}}}_{\mathit{c}}\left(\mathit{k}\right)$	z score	P value
HLA A	9.12E-3	-1.32E-2	2.04	2.06E-2
Class I	8.78E-3	-1.19E-2	1.91	2.83E-2
MICB-LST1	8.66E-3	-1.09E-2	1.78	3.79E-2
HLA B	8.19E-3	-1.11E-2	1.75	4.05E-2
HLA C	9.12E-3	-9.96E-3	1.72	4.24E-2
Class III	8.84E-3	-8.59E-3	1.59	5.57E-2
DQB1	1.00E-3	-7.28E-3	1.57	5.80E-2
DRB1	1.00E-3	-7.28E-3	1.57	5.80E-2
Class II	9.70E-3	-6.27E-3	1.47	7.10E-2
DPB1	9.58E-3	-2.87E-3	1.13	1.30E-1

Tests of European ancestry association with MS using test statistic for admixture mapping, sorted by P value. The column ${\stackrel{-}{z}}_{l,d}\left(k\right)-{\stackrel{-}{q}}_d\left(k\right)$ represents difference in average local and global European ancestry (k) proportions for cases d. The column ${\stackrel{-}{z}}_{l,c}\left(k\right)-{\stackrel{-}{q}}_c\left(k\right)$ is defined similarly as ${\stackrel{-}{z}}_{l,d}\left(k\right)-{\stackrel{-}{q}}_d\left(k\right)$ for controls c. The z score is the admixture mapping test statistic calculated as described in Materials and Methods. Adj P value is Bonferroni-adjusted p value.