Table 3. European ancestry association with MS at regions of the MHC in Hispanics.

MHC Region	${\stackrel{-}{\mathit{z}}}_{\mathit{l},\mathit{d}}\left(\mathit{k}\right)-{\stackrel{-}{\mathit{q}}}_{\mathit{d}}\left(\mathit{k}\right)$	${\stackrel{-}{\mathit{z}}}_{\mathit{l},\mathit{c}}\left(\mathit{k}\right)-{\stackrel{-}{\mathit{q}}}_{\mathit{c}}\left(\mathit{k}\right)$	z score	P value
Class I	-5.18E-2	-8.48E-2	1.57	5.76E-2
HLA A	-5.06E-2	-8.39E-2	1.55	6.11E-2
HLA C	-5.83E-2	-9.04E-2	1.51	6.51E-2
HLA B	-5.98E-2	-8.89E-2	1.38	8.43E-2
Class III	-5.09E-2	-7.55E-2	1.22	1.12E-1
MICB-LST1	-6.29E-2	-8.60E-2	1.11	1.34E-1
DQB1	-4.60E-2	-6.72E-2	1.02	1.54E-1
DRB1	-4.60E-2	-6.72E-2	1.02	1.54E-1
Class II	-4.00E-2	-5.32E-2	0.66	2.54E-1
DPB1	-2.76E-2	-2.91E-2	0.07	4.71E-1

Tests of European ancestry association with MS using test statistic for admixture mapping, sorted by P value. The column ${\stackrel{-}{z}}_{l,d}\left(k\right)-{\stackrel{-}{q}}_d\left(k\right)$ represents difference in average local and global European (k) ancestry proportions for cases d. The quantity ${\stackrel{-}{z}}_{l,c}\left(k\right)-{\stackrel{-}{q}}_c\left(k\right)$ is defined similarly for controls c. The z score is the admixture mapping test statistic calculated as described in Materials and Methods.