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. 2019 Jan 17;15(1):e1007808. doi: 10.1371/journal.pgen.1007808

Table 4. European ancestry association with MS at regions of the MHC in Asian Americans.

MHC Region z-l,d(k)-q-d(k) z-l,c(k)-q-c(k) z score P value
DQB1 -1.60E-2 5.98E-2 -1.67 4.80E-2
DRB1 -1.60E-2 5.98E-2 -1.67 4.80E-2
HLA A -3.94E-2 3.21E-2 -1.56 5.94E-2
Class II -1.67E-2 5.35E-2 -1.52 6.39E-2
Class III -7.52E-3 5.83E-2 -1.48 7.00E-2
DPB1 -2.38E-2 4.32E-2 -1.43 7.69E-2
MICB-LST1 -8.18E-3 5.37E-2 -1.36 8.62E-2
Class I -1.90E-2 4.07E-2 -1.33 9.24E-2
HLA B -3.69E-4 5.28E-2 -1.14 1.27E-1
HLA C -3.69E-4 5.27E-2 -1.14 1.27E-1

Tests of European ancestry association with MS using test statistic for admixture mapping, sorted by P value. The column z-l,d(k)-q-d(k) represents difference in average local and global European (k) ancestry proportions for cases d. The quantity z-l,c(k)-q-c(k) is defined similarly for controls c. The z score is the admixture mapping test statistic calculated as described in Materials and Methods.