Table 8. HLA-DRB1*15:01 of European origin confers greater risk of MS compared to DRB1*15:01 of African origin.
HLA-DRB1*15:01 Ancestry | Case (n) | Control (n) | |
---|---|---|---|
European | 129 | 191 | 319 |
African | 43 | 137 | 180 |
171 | 328 | 499 |
Two-by-two table of counts of HLA-DRB1*15:01 alleles by ancestry and case/control status. The HLA-DRB1*15:01 allele passed imputation quality score (R2 > 0.80) and had allele frequency greater than 0.005. Alleles that are not completely European or African were removed.