Comparison 5. Complex multivitamin versus control.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Overall cognitive functioning	1		Mean Difference (Random, 95% CI)	Subtotals only
1.1 > 2‐5 years of supplementation	1	5947	Mean Difference (Random, 95% CI)	0.04 [‐0.09, 0.17]
1.2 > 5‐10 years of supplementation	1	2324	Mean Difference (Random, 95% CI)	0.12 [‐0.14, 0.38]
2 Episodic memory	2		Mean Difference (Random, 95% CI)	Subtotals only
2.1 3‐12 months of supplementation	1	124	Mean Difference (Random, 95% CI)	33.17 [‐28.12, 94.46]
2.2 > 2‐5 years of supplementation	1	5942	Mean Difference (Random, 95% CI)	‐0.01 [‐0.05, 0.03]
2.3 > 5‐10 years of supplementation	1	2324	Mean Difference (Random, 95% CI)	‐0.01 [‐0.07, 0.05]
3 Executive function	1		Mean Difference (Random, 95% CI)	Subtotals only
3.1 > 2‐5 years of supplementation	1	5942	Mean Difference (Random, 95% CI)	‐0.02 [‐0.33, 0.29]
3.2 > 5‐10 years of supplementation	1	2324	Mean Difference (Random, 95% CI)	‐0.22 [‐0.65, 0.21]
4 Speed of processing	1		Mean Difference (Random, 95% CI)	Subtotals only
4.1 3‐12 months of supplementation	1	127	Mean Difference (Random, 95% CI)	‐14.71 [‐57.22, 27.80]