Hooper 2011.

Methods	Conference abstract of a single‐centre, parallel‐group RCT
Participants	10,727 participants admitted to a tertiary care centre were monitored by an electronic application to detect modified SIRS criteria (defined as 2 out of 4 SIRS criteria but mandates that white blood cell count or temperature be abnormal). 680 patients met modified SIRS criteria at some point during their hospitalisation and underwent analysis. Age: 57 years (median) Gender: not stated Unclear where the trial took place, but presume USA
Interventions	Physician alerts (n = not stated): no further details reported Control group receiving usual care (n = not stated): no further details reported
Outcomes	Time from ICU admission to modified SIRS criteria Receipt of new antibiotics after reaching modified SIRS criteria
Notes	We contacted study author by email to check relationship between this study and Hooper 2010, and Hooper 2012. Email bounced back and we could not find up‐to‐date contact information. States that the abstract is funded by: NIH 1RC1LM010310‐01 Declaration of interest: not stated
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	States that participants were randomized, but methods for randomization not stated
Allocation concealment (selection bias)	Unclear risk	Not stated
Blinding of participants and personnel (performance bias) All outcomes	Unclear risk	Not stated
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	Not stated
Incomplete outcome data (attrition bias) All outcomes	Unclear risk	Not stated
Selective reporting (reporting bias)	Unclear risk	No other sources of bias identified
Other bias	Low risk	Not identified