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. Author manuscript; available in PMC: 2019 Jan 30.
Published in final edited form as: JAMA Psychiatry. 2016 May 1;73(5):506–514. doi: 10.1001/jamapsychiatry.2016.0144

Table.

Genome-Wide Significant Schizophrenia-Associated DMPsa

Illumina Gene Annotation Genes Within 50 kb of Associated CpG Discovery Set(n = 1334)
 Replication Set(n = 497)
Probe Chromosome Position Δ P Value FDR Δ P Value
cg04792777 14 106322429 NA IGHE; IGHG1; IGHD; KIAA0125; MIR4507; MIR4538; MIR4537; MIR4539 −0.007 1.06E–07 0.01 −0.008 E–<.001
cg13092108 1 26857284 RPS6KA1 RPS6KA1; MIR1976 −0.008 1.16E–07 0.01 −0.009 4.38E–05
cg04962621 16 4714733 MGRN1 MGRN1; NUDT16L1; ANKS3 −0.009 1.32E–07 0.01 −0.007 6.95E–05
cg13997435 1 153538406 S100A2 S100A6; S100A5; S100A4; S100A3; S100A2; S100A16; S100A14 −0.007 3.26E–07 0.01 −0.005 2.77E–02
cg26385126 12 124912021 NCOR2 NCOR2 0.006 4.99E–07 0.01 0.010 3.91E–07
cg07458272 19 34744396 KIAA0355 LSM14A; KIAA0355 0.010 5.39E–07 0.01 0.007 2.10E–02
cg13549638 17 78860076 RPTOR RPTOR 0.013 6.70E–07 0.01 0.008 3.72E–02
cg10975863 14 68830704 RAD51B RAD51B 0.011 6.90E–07 0.01 0.010 1.62E–02
cg22891595 3 193570256 NA AK091265 (cDNA) 0.011 6.94E–07 0.01 0.006 4.98E–02
cg06996599 6 30619232 C6orf136 PPP1R10; MRPS18B; ATAT1; DHX16; PPP1R18; NRM; MDC1 0.007 9.39E–07 0.02 0.006 3.28E–03
cg23387863 15 77472416 PEAK1 PEAK1 0.010 1.02E–06 0.02 0.011 6.62E–04
cg25323444 7 2111060 MAD1L1 MAD1L1 0.011 1.07E–06 0.02 0.011 2.32E–04
cg11621113 19 12776725 MAN2B1 ZZNF791; MAN2B1; DHPS; FBXW9; WDR83; TNPO2 −0.008 1.09E–06 0.02 −0.013 8.72E–10
cg23009327 19 1630248 TCF3 MBD3; UQCR11; TCF3 0.010 1.32E–06 0.02 0.007 7.92E–03
cg12939085 11 67166104 PPP1CA POLD4; CLCF1; RAD9A; PPP1CA; TBC1D10C; CARNS1; RPS6KB2; PTPRCAP; CORO1B 0.008 2.45E–06 0.02 0.006 4.65E–03

Abbreviations: DMP, differentially methylated positions; FDR, false discovery rate; NA, not available.

a

Listed are the top 15 replicated results. All replicated DMPs with an FDR of less than 0.20 are listed in eTable 3 in the Supplement.