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Chloroquine reduces local and systemic inflammation in acute pancreatitis. Chloroquine treatment led to a significant reduction in amylase (A) and trypsin (B) activity. The systemic inflammatory response to acute pancreatitis was assessed by measuring HMGB1 (C) and IL-6 (D). Chloroquine treatment led to a significant reduction in both of these circulating inflammatory markers. *p < 0.05.
