Table 3.
Association between APOL1 G1-G2 variant alleles and incident clinical AIDS.
| No. APOL1 G1-G2 risk alleles | n | RH | 95% CI | P |
|---|---|---|---|---|
| 0 (reference) | 88 | 1 | – | 1 |
| 1 (1 vs. 0) | 110 | 1.11 | 0.52–2.34 | 0.79 |
| 2 (2 vs. 0) | 29 | 0.87 | 0.16–4.74 | 0.87 |
| Additive (2 vs. 1. vs. 0) | 1.09 | 0.59–2.02 | 0.79 | |
| Dominant (2 or 1 vs. 0) | 1.07 | 0.51–2.24 | 0.85 | |
| Recessive (2 vs. 1 or 0) | 1.24 | 0.28–5.40 | 0.78 |
There were no associations between APOL1 kidney risk alleles and incident AIDS. Cox model results, adjusted for age, sex, HLA-B*57, and HLA Class I homozygosity.