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. 2019 Jan 24;10:2. doi: 10.3389/fphar.2019.00002

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Copyright © 2019 Park, Kang, Nam, Suh and Chang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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PSM-04 increased the expression of SOD-2 in the brain of 5xFAD mice. Representative Western blot demonstrating protein expression levels of SOD-2 in the hippocampus of each group. (A) Representative blot showing that SOD-2 protein levels increased in the hippocampal tissue lysates of PSM-04-treated Tg mice compared with those of the non-treated Tg mice. (B) The relative SOD-2 protein levels were shown as a ratio versus to the control (Tg-v). The statistical analyses were performed by one-way ANOVA, and data are presented as the means ± SEM. ^#p < 0.05 vs. WT-v. ^∗p < 0.01 and ^∗∗p < 0.01 vs. Tg-v. WT-v (n = 8); WT-PP-5 (n = 9); Tg-v (n = 7); Tg-PP-5 (n = 6); Tg-PP-10 (n = 6); Tg-DP (n = 5).