. 2019 Jan 30;9:929. doi: 10.1038/s41598-018-37481-y

Table 5.

Comparison of mean temperature and mean humidity for different viruses.

	Temperature/Humidity	IBV	HMPV	Adenovirus	HPIV-3	HPIV-1	Rhinovirus	HPIV-2	RSV
IAV	T	−0.45	0.69	−2.10***	−2.63***	−2.31***	−2.19***	−1.50*	0.45
IAV	H	−1.23	−1.18	1.26	3.07***	0.38	1.37**	0.72	−1.03
IBV	T		1.13*	−2.55***	−3.08***	−2.75***	−2.64***	−1.94**	0.01
IBV	H		0.05	0.02	1.84	−0.85	0.14	−0.51	−2.26**
HMPV	T			−1.42***	−1.95***	−1.62***	−1.51***	−0.81	1.14***
HMPV	H			0.07	1.89**	−0.81	0.19	−0.46	−2.21***
Adenovirus	T				−0.53	0.20	−0.09	−0.61	−2.56***
Adenovirus	H				1.81**	0.88	0.11	0.53	2.28***
HPIV-3	T					−0.33	−0.44	−1.14	−3.09***
HPIV-3	H					2.69***	1.70**	2.35	4.10***
HPIV-1	T						0.11	−0.81	−2.76***
HPIV-1	H						0.99	−0.34	1.41
Rhinovirus	T							−0.70	−2.65***
Rhinovirus	H							0.65	2.40***
HPIV-2	T								−1.95***
HPIV-2	H								1.75

To determine which variable significantly affects transition from one virus to another, we calculated the differences in mean temperature and relative humidity of virus in column minus virus in row. e.g. a decrease in temperature from autumn to winter is associated with a change from HPIV-2 to RSV. T = Temperature Difference, H = Humidity difference. Results of ANOVA. Significant p values in bold (*p < 0.05; **p < 0.01; ***p < 0.001).