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. 2019 Jan 30;9:980. doi: 10.1038/s41598-018-37529-z

Table 2.

Incidence and risks of eGFR decline ≥30% over a 2-year follow-up period in older people.

Serum uric acid (mg/dL) Incidence Logistic Regression Analysis
No. of Events No. of Participants Crude Odds Ratio (95% CI) P Adjusted Odds Ratio (95% CI)a P
2.0–2.9 23 (4.4%) 522 2.07 (1.34–3.21) 0.001 1.69 (1.08–2.63) 0.021
3.0–3.9 64 (2.4%) 2,656 1.11 (0.84–1.47) 0.463 0.91 (0.68–1.20) 0.491
4.0–4.9 205 (2.7%) 7,708 1.23 (1.02–1.48) 0.032 1.10 (0.91–1.33) 0.319
5.0–5.9 241 (2.2%) 11,076 Reference Reference
6.0–6.9 233 (2.3%) 10,047 1.07 (0.89–1.28) 0.483 1.21 (1.00–1.45) 0.048
7.0–7.9 220 (3.4%) 6,435 1.59 (1.32–1.92) <0.001 1.91 (1.58–2.32) <0.001
8.0–8.9 103 (3.0%) 3,387 1.41 (1.12–1.78) 0.004 1.77 (1.38–2.26) <0.001
9.0–9.9 41 (3.1%) 1,344 1.41 (1.01–1.98) 0.043 1.61 (1.13–2.29) 0.008
≥10 60 (6.6%) 903 3.20 (2.39–4.28) <0.001 3.35 (2.45–4.59) <0.001

aAdjusted for age, sex, body mass index, smoking, alcohol drinking, comorbidities and all biochemical data in Table 1.

Abbreviation: CI, confidence interval; eGFR, estimated glomerular filtration rate.

SI conversion factors: To convert uric acid value to μmol/L, multiply by 59.485.