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. 2019 Jan 30;10:487. doi: 10.1038/s41467-019-08417-5

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — Mitotic chromosome binding predicts TF properties in interphase We propose that the MBF allows to predict TF non-specific DNA binding, which regulates TF mobility, on-rate and search efficiency, thus influencing genome occupancy. Modulation of chromatin accessibility at bound sites depends on genome-wide occupancy but even more so on pioneer activity