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. 2019 Jan 30;9:950. doi: 10.1038/s41598-018-37521-7

Figure 5.

Figure 5

p73 or AP2α knock-down rescues starvation-mediated sialyl Lewis X repression. (A) Starvation repressed sialyl Lewis X expression in HT29 cells infected with a scrambled shRNA (orange line, isotype control with cells infected with a control scrambled shRNA cultured with full serum; blue line, isotype control with cells infected with a control scrambled shRNA under starvation; green line, sialyl Lewis X staining with cells infected with a control scrambled shRNA cultured with full serum; red line, sialyl Lewis X staining with cells infected with a control scrambled shRNA cultured under starvation). (B) p73 knock down (p73 KD1 cells, as in Fig. 2D) rescued the starvation-mediated sialyl Lewis X repression (orange line, isotype control with p73 KD1 cells cultured with full serum; blue line, isotype control with p73 KD1 cells cultured under starvation; green line, sialyl Lewis X staining with p73 KD1 cells cultured with full serum; red line, sialyl Lewis X staining with p73 KD1 cells cultured under starvation). (C) AP2α knock down (AP2α KD1 cells, as in Fig. 2E) rescued starvation-mediated sialyl Lewis X repression (orange line, isotype control for AP2α KD1 cells cultured with full serum; blue line, isotype control for AP2α KD1 cells cultured under starvation; green line, sialyl Lewis X staining for AP2α KD1 cells cultured with full serum; red line, sialyl Lewis X staining for AP2α KD1 cells cultured under starvation).