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This graphical summary clarifies the most important findings of the presented investigation within the context of septic coagulopathy. PRR pattern recognition receptor, PAMP pathogen-associated molecular pattern, AT III antithrombin III, TF tissue factor, TAT thrombin–antithrombin complex, tPA tissue plasminogen activator, PAI-1 plasminogen activator inhibitor 1, TGA thrombin generation assay, COX cyclooxygenase
