Figure 3:

Clustering of HMP 16S rRNA datasets using Mash, Libra, and Simka. A total of 48 human metagenomic samples from the HMP clustered by Mash (A), Libra (B), or Simka using Jaccard-ab (C) and Bray-Curtis distances (D) from 16S rRNA sequencing runs. The samples were clustered using Ward's method on their distance scores. Mash, Simka, and Libra report distance in the same range (0–1). Heat maps showing the pairwise dissimilarity between samples were therefore scaled between 0 (green) and 1 (red). A key below the heat map colors the samples by body sites.