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. 2019 Feb 5;73(4):444–453. doi: 10.1016/j.jacc.2018.10.070

Table 3.

Clinical Outcomes in LAD-Deferred Patients

Unadjusted
Adjusted
iFR Group (n = 451) FFR Group (n = 421) Hazard Ratio (95% CI) p Value Hazard Ratio (95% CI) p Value
MACE (cardiovascular death, MI, unplanned revascularization) 11 (2.44) 23 (5.46) 0.47 (0.23–0.96) 0.04 0.46 (0.22–0.95) 0.04
Cardiovascular death 0 (0.00) 1 (0.24)
MACE (all-cause death, MI, unplanned revascularization) 15 (3.33) 27 (6.41) 0.54 (0.29–1.02) 0.06 0.53 (0.28–1.01) 0.05
All-cause death 4 (0.89) 5 (1.19) 0.76 (0.21–2.84) 0.69 0.77 (0.21–2.86) 0.69
MI 2 (0.44) 9 (2.14) 0.24 (0.05–1.11) 0.07 0.23 (0.05–1.07) 0.06
 Target vessel MI 1 (0.22) 6 (1.43) 0.16 (0.02–1.30) 0.09 0.15 (0.02–1.23) 0.08
 Nontarget vessel MI 0 (0.00) 2 (0.48)
 Periprocedural MI 1 (0.22) 1 (0.24) 1.00 (1.00–1.00) 1.00 1.00 (1.00–1.00) 1.00
Unplanned revascularization 10 (2.22) 21 (4.99) 0.45 (0.21–0.95) 0.04 0.44 (0.21–0.93) 0.03
 TVR 7 (1.55) 15 (3.56) 0.44 (0.18–1.07) 0.07 0.42 (0.17–1.04) 0.06
 Non-TVR 3 (0.67) 6 (1.43) 0.47 (0.12–1.88) 0.29 0.47 (0.12–1.88) 0.28

Values are n (%) unless otherwise indicated.

CI = confidence interval; MACE = major adverse cardiac events; MI = myocardial infarction; TVR = target vessel revascularization; other abbreviations as in Table 1.

Statistically significant p values.