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. 2018 Nov 14;42(1):28–35. doi: 10.14348/molcells.2018.0380

Fig. 4. FLP-18 neuropeptide and NPR-1 neuropeptide receptor are required for pheromone-mediated str-3 repression.

Fig. 4

(A) Representative images of flp-18, npr-1, and flp-18;npr-1 mutants expressing the str-3p::gfp transgene in the ASI neurons at the L1 (left two panels) and adult stage (right two panels) upon exposure to mixtures of 1 μM ascaroside pheromone. (B–C) Relative GFP levels of str-3p::gfp expression in flp-18, npr-1, and flp-18;npr-1 mutants at the L1 (B) and adult stage (C) upon exposure to mixtures of 1 μM ascaroside pheromone. (D–E) Relative GFP levels of str-3p::gfp expression in flp-18 mutants expressing flp-18 genomic DNA driven by its own promoter upon exposure to mixtures of 1 μM ascaroside pheromone. n≥ 30 for each. Error bars represent the SEM. *, #, and † indicate different from the controls (absence of pheromone, wild-type animals, and no transgene, respectively) at P < 0.001 (Bonferroni t -test). The scale bar represents 10 μm.