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. 2019 Jan 7;42(1):8–16. doi: 10.14348/molcells.2018.0436

Fig. 3. Diagram of β-catenin protein domains and hotspot mutations.

Fig. 3

(A) A schematic diagram of the β-catenin protein and mRNA. UTR, untranslated region; CDS, coding sequence; ATG, translation start codon; TAA, translation stop codon. (B) Exon 3 hotspot mutations of CTNNB1 are marked on the lollipop plot downloaded from the MSK-IMPACT pan-cancer study on cBioportal. Deep deletions near Exon 3 of CTNNB1 pre-mRNA are indicated as red lines. Deletion data were obtained from metastatic colorectal cancer study (MSK) on cBioportal.