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. Author manuscript; available in PMC: 2019 Mar 1.
Published in final edited form as: Am J Transplant. 2017 Dec 18;18(3):632–641. doi: 10.1111/ajt.14597

Table 1:

Study Sample Characteristics

Shipped Exchange In-Center Exchange p-valb Other Non-Exchange p-valb

n=1267 n=205 n=4800

Cold Ischemia Time (hours) a 9.3 (6.9–12.2) 1.0 (0.8–1.5) <0.001 0.9 (0.5–1.0) <0.001

Recipient: Age a 50 (39–60) 50 (39–60) >0.9 50 (41–59) 0.6

   Female 599 (47%) 74 (36%) <0.01 1557 (32%) <0.001

   Diabetic 307 (24%) 53 (26%) 0.6 1349 (28%) <0.01

   Primary Diagnosis: DM 232 (18%) 46 (23%) 0.07 1078 (22%) <0.001
         GN 412 (33%) 60 (29%) 1401 (29%)
         PKD 158 (12%) 30 (15%) 824 (17%)
         Congenital 48 (3.8%) 1 (0.5%) 108 (2.3%)
         Other 417 (33%) 68 (33%) 1389 (29%)

   Years on RRT a 1.4 (0.2–2.9) 1.8 (0.6–3.6) 0.048 0.5 (0–1.6) <0.001

   Previous Transplant 358 (28%) 35 (17%) 0.001 504 (11%) <0.001

   Pre-emptive Transplant 306 (24%) 40 (20%) 0.1 1818 (38%) <0.001

   Black (vs non-black) 211 (17%) 50 (24%) <0.01 554 (12%) <0.001

   PRA at Transplant: 0 522 (41%) 119 (58%) <0.001 3291 (69%) <0.001
           1–10 67 (5.3%) 14 (6.8%) 327 (6.8%)
           11–79 347 (27%) 39 (19%) 661 (14%)
           ≥80 324 (26%) 26 (13%) 111 (2.3%)
           missing 7 (0.6%) 7 (3.4%) 410 (8.5%)

   BMI a 27 (23–31) 26 (23–31) 0.3 27 (24–31) <0.01

Donor: Age a 45 (35–52) 48 (38–56) <0.01 45 (36–53) 0.02

   Female 789 (62%) 126 (62%) 0.8 3217 (67%) <0.01

   Black (vs non-black) 137 (11%) 24 (12%) 0.7 385 (8.0%) <0.01

   LD KDPI a 12.2 (−0.84 – 25.0) 12.0 (−0.51 – 31.3) 0.4 15.2 (1.86 – 30.1) <0.001

HLA Mismatches: 0 9 (0.7%) 0 0.08 17 (0.4%) <0.001
        1 29 (2.3%) 3 (1.5%) 38 (0.8%)
        2 81 (6.4%) 10 (4.9%) 207 (4.3%)
        3 198 (16%) 38 (19%) 633 (13%)
        4 340 (27%) 44 (22%) 1348 (28%)
        5 404 (32%) 68 (33%) 1620 (34%)
        6 182 (14%) 41 (20%) 907 (19%)
        missing 22 (1.7%) 0 30 (0.6%)

Year of Transplanta 2013 (2012–2014) 2012 (2010 – 2014) <0.001 2012 (2010 – 2014) <0.001
a

median (IQR). CIT missing in 30 (15%) in-center exchanges, 21 (1.7%) of shipped exchanges, and none of the other non-exchanges. Recipient BMI missing in 1 (0.5%) in-center exchange, 4 (0.3%) of shipped exchanges, and 150 (3.2%) of the other non-exchanges. LD KDPI: Live-donor kidney donor profile index. LD KDPI missing in 3 in-center exchanges, 48 shipped exchanges, 242 of other non-exchanges.

b

P-values are compared to the Shipped Exchange group only.